Mixed culture cytopathogenicity: a new test for growth of murine leukemia viruses in tissue culture.
نویسندگان
چکیده
Tissue culture cells of a Rous virus-induced rat tumor undergo syncytium formation when placed in contact with mouse embryo cell cultures infected with murine leukemia viruses. This phenomenon can be used as a cytopathic end point for isolating and titrating these viruses in tissue culture. The principle should be applicable to detection of leukemia viruses of other species.
منابع مشابه
Lack of syncytium formation by a type C virus-producing XC cell line in the mixed culture cytopathogenicity test.
XC cells, derived from a Rous sarcoma virus-induced Wistar strain rat tumor, form syncytia when cultured in the presence of murine leukemia virus-producing mouse cells. However, one XC cell culture (designated as XC-v cells), found to produce type C virus particles, fails to form syncytia in the presence of murine leukemia virus-producing mouse cells. Coculture of XC-v cells and XC cells negati...
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XC cells, derived from a Rous sarcoma virus-induced Wistar strain rat tumor, form syncytia when cultured in the presence of murine leukemia virus-producing mouse cells. However, one XC cell culture (designated as XC-v cells), found to produce type C virus particles, fails to form syncytia in the presence of murine leukemia virus-producing mouse cells. Coculture of XC-v cells and XC cells negati...
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ورودعنوان ژورنال:
- Proceedings of the National Academy of Sciences of the United States of America
دوره 63 3 شماره
صفحات -
تاریخ انتشار 1969